article-title: Drug-induced changes in connectivity to midbrain dopamine cells revealed by rabies monosynaptic tracing

article-type: research-article


article-title: The role of ATP synthase subunit e (ATP5I) in mediating the metabolic and antiproliferative effects of metformin in cancer cells


article-title: Stranded short nascent strand sequencing reveals the topology of DNA replication origins in <i>Trypanosoma brucei</i>


article-title: Bilateral equalization of synaptic output in olfactory glomeruli of <i>Xenopus</i> tadpoles


article-title: Adrenomedullin restores the human cortical interneurons migration defects induced by hypoxia


article-title: Tumors mimic the niche to inhibit neighboring stem cell differentiation


article-title: Spatial and longitudinal tracking of enhancer-AAV vectors that target transgene expression to injured mouse myocardium

article-type: tools-resources


article-title: Subregional activity in the dentate gyrus is amplified during elevated cognitive demands


article-title: Identification of the regulatory elements and protein substrates of lysine acetoacetylation


article-title: Effort produces after-effects costly for others but valued for self


article-title: A meta-analysis suggests that TMS targeting the hippocampal network selectively improves episodic memory


article-title: The dual molecular identity of vestibular kinocilia bridges structural and functional traits of primary and motile cilia


article-title: Drosophila ryanodine receptor gene triggers functional and developmental muscle properties and could be used to assess the impact of human RYR1 mutations


article-title: Examining the role of lipids in hearing

article-type: insight


article-title: Locus coeruleus modulation of prefrontal dynamics during attentional switching in mice


article-title: A context-free model of savings in motor learning


article-title: The long non-coding RNA <i>Dreg1</i> is required for optimal ILC2 development


article-title: Characterisation of cold-selective lamina I spinal projection neurons in the mouse


article-title: Modeling flexible behavior with remapping-based hippocampal sequence learning


article-title: Dissociable neural substrates of integration and segregation in exogenous attention


article-title: Intravital calcium imaging of meningeal macrophages reveals niche-specific dynamics and aberrant responses to brain hyperexcitability


article-title: Physiological febrile heat stress increases cytoadhesion through increased protein trafficking of <i>Plasmodium falciparum</i> surface proteins into the red blood cell


article-title: An altered cell-specific subcellular distribution of translesion synthesis DNA polymerase kappa (POLK) in aging mouse neurons


article-title: Science under threat around the world

article-type: feature


article-title: Drift in individual behavioral phenotype as a strategy for unpredictable worlds


article-title: Cortical motor activity modulates respiration and reduces apnoea in neonates


article-title: HIV-1 envelope glycoprotein modulates CXCR4 clustering and dynamics on the T cell membrane


article-title: Functional imaging of nine distinct neuronal populations under a miniscope in freely behaving animals


article-title: Endogenous corazonin signaling modulates the post-mating switch in behavior and physiology in females of the brown planthopper and <i>Drosophila</i>


article-title: Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin-dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology


article-title: Adult-neurogenesis allows for representational stability and flexibility in early olfactory system

article-type: short-report


article-title: Cross-modal interaction of human alpha activity does not reflect inhibition of early sensory processing in a frequency-tagging study using EEG and MEG


article-title: Regime shift detection and neurocomputational substrates for under and overreactions to change


article-title: Recombination shapes the diversification of the <i>wtf</i> meiotic drivers


article-title: Age-dependent H3K9 trimethylation by dSetdb1 impairs mitochondrial UPR leading to degeneration of olfactory neurons and loss of olfactory function in <i>Drosophila</i>


article-title: Prediction of SARS-CoV-2 transmission dynamics based on population-level cycle threshold values: An epidemic transmission and machine learning modeling study


article-title: Neural representation of time across complementary reference frames


article-title: Mettl5 coordinates protein production and degradation of PERIOD to regulate sleep in Drosophila


article-title: Adaptive variation in avian eggshell gas conductance and structure across elevational gradients?


article-title: A novel 3D visualization method in mice identifies the periportal lamellar complex (PLC) as a key regulator of hepatic ductal and neuronal branching morphogenesis


article-title: How membranes shape up for lipid transfer


article-title: Prolonged oscillating preoptic area kisspeptin neuron activity underlies the preovulatory luteinizing hormone surge in mice


article-title: RadD from <i>Fusobacterium nucleatum</i> engages NKp46 to promote antitumor cytotoxicity


article-title: HER2-driven mammary tumorigenesis enhances bioenergetics despite reductions in mitochondrial content


article-title: Dynamic architecture of mycobacterial outer membranes revealed by all-atom simulations


article-title: Continuous flash suppression of neural responses and population orientation coding in macaque V1


article-title: Fully computational design of PAM-relaxed <i>Staphylococcus aureus</i> Cas9 with expanded targeting capability using UniDesign


article-title: Canonical neurodevelopmental trajectories of structural and functional manifolds


article-title: Natural xanthones as α-Mangostin induce vasorelaxation involving key gating residues in the S6 domain of BK channels


article-title: Auditory perception and neural representation of temporal features are altered by age but not by cochlear synaptopathy


article-title: Mitochondrial ETF insufficiency drives neoplastic growth by selectively optimizing cancer bioenergetics


article-title: Real-time transcriptomic profiling in distinct experimental conditions


article-title: Collective epithelial migration mediated by the unbinding of hexatic defects


article-title: Herbivorous insects independently evolved salivary effectors to regulate plant immunity by destabilizing the malectin-LRR RLP NtRLP4


article-title: Investments in photoreceptors compete with investments in optics to determine eye design


article-title: Hugin-AstA circuitry is a novel central energy sensor that directly regulates sweet sensation in <i>Drosophila</i> and mouse


article-title: Human adherent cortical organoids in a multi-well format


article-title: Defects in lipid homeostasis reflect the function of TANGO2 in phospholipid and neutral lipid metabolism


article-title: Adapting clinical chemistry plasma as a source for liquid biopsies


article-title: Evidence of off-target probe binding affecting 10x Genomics Xenium gene panels compromise accuracy of spatial transcriptomic profiling


article-title: Unbend, correction of local beam-induced sample motion in cryo-EM images using a 3D spline model

article-type: research-advance


article-title: Bivalent mRNA booster encoding virus-like particles elicits potent polyclass receptor-binding domain antibodies in pre-vaccinated mice


article-title: On-demand seizures facilitate rapid screening of therapeutics for epilepsy


article-title: The FAM53C/DYRK1A axis regulates the G1/S transition of the cell cycle


article-title: Prickle and Ror modulate Dishevelled-Vangl interaction to regulate non-canonical Wnt signaling during convergent extension in <i>Xenopus</i>


article-title: Towards a unified molecular mechanism for ligand-dependent activation of NR4A-RXR heterodimers


article-title: scRNA-seq and scATAC-seq reveal that Sertoli cell mediates spermatogenesis disorders through stage-specific communications in non-obstructive azoospermia


article-title: Distinct functions of cardiac β-adrenergic receptors in the T-tubule vs<i>.</i> outer surface membrane


article-title: Inference of germinal center evolutionary dynamics via simulation-based deep learning


article-title: Interrogating the structure and function of the human voltage-gated proton channel (hHv1) with a fluorescent noncanonical amino acid


article-title: AFD thermosensory neurons mediate tactile-dependent locomotion modulation in <i>C. elegans</i>


article-title: Single-cell lineage tracing identifies hemogenic endothelial cells in the adult mouse bone marrow


article-title: Distinct mechanisms of inhibition of Kv2 potassium channels by tetraethylammonium and RY785


article-title: Does the brain really know what word is coming next?


article-title: B cell expression of an enzymatic intermediary in ether lipid biosynthesis promotes antibody responses and germinal center size


article-title: The olfactory receptor SNIF-1 mediates foraging for leucine-enriched diets in <i>C. elegans</i>


article-title: Horizontally transferred cell-free chromatin particles function as autonomous ‘satellite genomes’ and vehicles for transposable elements within host cells


article-title: Teaching early-career researchers how to respond to peer reviewers


article-title: HEB collaborates with TCR signaling to upregulate <i>Id3</i> and enable γδT17 cell maturation in the fetal thymus


article-title: Colony demographics shape nest construction in <i>Camponotus fellah</i> ants


article-title: Multiple functions of cerebello-thalamic neurons in learning and offline consolidation of a motor skill in mice


article-title: Clathrin-independent endocytosis and retrograde transport in cancer cells tune immune synapse organization and CD8 T cell response


article-title: SMC complex unidirectionally translocates DNA by coupling segment capture with an asymmetric kleisin path


article-title: A quantitative in vivo CRISPR-imaging platform identifies regulators of hyperplastic and hypertrophic adipose morphology in zebrafish


article-title: Earliest evidence of elephant butchery at Olduvai Gorge (Tanzania) reveals the evolutionary impact of early human megafaunal exploitation


article-title: Antibiotic potentiation and inhibition of cross-resistance in pathogens associated with cystic fibrosis


article-title: PPIscreenML is a method for structure-based screening of protein-protein interactions using AlphaFold


article-title: Orderly mitosis shapes interphase genome architecture


article-title: Single-cell co-mapping reveals relationship between chromatin state and gene expression in early zebrafish development


article-title: Modeling the hallucinatory effects of classical psychedelics in terms of replay-dependent plasticity mechanisms


article-title: Prior cocaine use disrupts identification of hidden states by single units and neural ensembles in orbitofrontal cortex


article-title: Brain-wide mapping of layer-specific functional connectivity in the human cortex at 3T using draining-vein-suppressed fMRI


article-title: Taking the biology seriously makes models better


article-title: How individual vigor shapes human–human physical interaction


article-title: Dimorphic neural network architecture prioritizes sexual-related behaviors in male <i>Caenorhabditis elegans</i>


article-title: The robust, high-throughput, and temporally regulated roxCre and loxCre reporting systems for genetic modifications in vivo


article-title: Alpha-band phase modulates perceptual sensitivity by changing internal noise and sensory tuning


article-title: Structural mechanisms of pump assembly and drug transport in the AcrAB–TolC efflux system